It is prescribed for the husband to pray Istikharah about divorcing his wife if doing so is permissible. Similarly it is permissible for the wife to pray Istikharah about asking for a divorce, if doing so is because of a reason that makes it permissible to seek divorce. Apart from that, it is not prescribed to pray Istikharah about divorce.

If istikharah has to do with an immediate matter that cannot be delayed until the time when prayer is not allowed is over, then it may be done. If istikharah is for something that may be delayed, then it must be delayed.

Istikharah prayer is a Sunnah. Istikharah means seeking guidance as to what Allah knows is the best and most appropriate choice. Istikharah implies submission to the command of Allah and a practical demonstration that one has no power and no strength of one’s own.